2011
菅澤 薫(神戸大学)
Fischer, ES., Scrima, A., Böhm, K., Matsumoto, S., Lingaraju, GM., Faty, M., Yasuda, T., Cavadini, S., Wakasugi, M., Hanaoka, F., Iwai, S., Gut, H., Sugasawa, K., and *Thomä, NH.
The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.
Cell 147, 1024-1039 (2011)
Yanagihara, H., Kobayashi, J., Tateishi, S., Kato, A., Matsuura, S., Tauchi, H., Yamada, K., Takezawa, J., Sugasawa, K., Masutani, C., Hanaoka, F., Weemaes, CM., and Mori, T., Zou, L., and *Komatsu, K.
NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis.
Mol. Cell 43, 788-797 (2011)
柳澤 純(筑波大学)
Goto, N., Hiyoshi, H., Ito, I., Tsuchiya, M., Nakajima, Y., and *Yanagisawa, J.
Estrogen and antiestrogens alter breast cancer invasiveness by modulating TGF-b signaling pathway.
Cancer Sci. 102, 1501-1508 (2011)
Kajiro, M., Tsuchiya, M., Kawabe, Y., Furumai, R., Iwasaki, N., Hayashi, Y., Katano, M., Nakajima, Y., Goto, N., Watanabe, T., Murayama, A., Oishi, H., Ema, M., Takahashi, S., Kishimoto, H., and *Yanagisawa, J.
The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis.
PLoS One 6, e25871 (2011)
清水 敏之(東京大学)
Ohto, U., Miyake, K., and *Shimizu, T.
Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J. Mol. Biol. 413, 815-825 (2011)
Kokabu, Y., Murayama, Y., Kuwabara, N., Oroguchi, T., Hashimoto, H., Tsutsui, Y., Nozaki, N., Akashi, S., Unzai, S., Shimizu, T., Iwasaki, H., Sato, M., and *Ikeguchi, M.
The fission yeast Swi5-Sfr1 complex, an activator of Rad51 recombinase, forms an extremely elongated Dogleg-shaped structure.
J. Biol. Chem. 286, 43569-43576 (2011)
本橋 ほづみ(東北大学)
Uruno, A., and *Motohashi, H.
The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
Nitric Oxide 25, 153-160 (2011)
矢作 直也(筑波大学)
Kumadaki, S., Karasawa, T., Matsuzaka, T., Ema, M., Nakagawa, Y., Nakakuki, M., Saito, R., Yahagi, N., Iwasaki, H., Sone, H., Takekoshi, K., Yatoh, S., Kobayashi, K., Takahashi, A., Suzuki, H., Takahashi, S., Yamada, N., and *Shimano, H.
Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.
J. Biol. Chem. 286, 40835-40846 (2011)