2012
深水 昭吉(筑波大学)、研究分担者;高橋 秀和(岡山大学)
Takahashi, H., Sun, X., Hamamoto, M., Yashiroda, Y., and*Yoshida, M.
The SAGA Histone Acetyltransferase Complex Regulates Leucine Uptake through the Agp3 Permease in Fission Yeast.
J. Biol. Chem. 287, 38158-38167 (2012)
Hashimoto, T., Perlot, T., Rehman, A., Trichereau, J., Ishiguro, H., Paolino, M., Sigl, V., Hanada, T., Hanada, R., Lipinski, S., Wild, B, Camargo, SM., Singer, D., Richter, A., Kuba, K., Fukamizu, A., Schreiber, S., Clevers, H., Verrey, F., *Rosenstiel, P., and *Penninger, JM.
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Nature 487, 477-481 (2012)
Ozcan, L., Wong, CC., Li, G., Xu, T., Pajvani.,U., Park, SK., Wronska, A., Chen, BX., Marks, AR., Fukamizu, A., Backs, J., Singer, HA., Yates, JR 3rd., Accili, D., and *Tabas, I.
Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity.
Cell Metab. 15, 739-751 (2012)
Sakamaki, JI., Daitoku, H., Kaneko, Y., Hagiwara, A., Ueno, K., and *Fukamizu, A.
GSK3 regulates gluconeogenic gene expression through HNF4α and FOXO1.
J. Recept. Signal Transduct. 32, 96-101 (2012)
五十嵐 和彦(東北大学)
Li, J., Shiraki, T., and *Igarashi, K.
Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism.
FEBS Lett. 586(4), 448-454 (2012)
中尾 光善(熊本大学)
*Hino, S., Sakamoto, A., Nagaoka, K., Anan, K., Wang, Y., Mimasu, S., Umehara, T., Yokoyama, S., Kosai, K., and *Nakao, M.
FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure.
Nat. Commun. 3, Article number 758 (2012)
柳澤 純(筑波大学)
Kuwabara, N., Oyama, T., Tomioka, D., Ohashi, M., Yanagisawa, J., Shimizu, T., and *Miyachi, H.
Peroxisome Proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: Phenypropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.
J. Med. Chem. 55, 893-902 (2012)
清水 敏之(東京大学)
Ohto, U., Usui, K., Ochi, T., Yuki, K., Satow, Y., and *Shimizu, T.
Crystal Structure of Human β-Galactosidase: The Structural Basis of GM1 Gangliosidosis and Morquio B Diseases.
J. Biol. Chem. 287, 1801-1812 (2012)
Usui, K., *Ohto, U., Ochi, T., Shimizu, T., and *Satow, Y.
Expression, purification, crystallisation and preliminary X-ray crystallographic analysis of human β-Galactosidase.
Acta Crystallogr. F68, 73-77 (2012)
本橋 ほづみ(東北大学)
Mitsuishi, Y., Taguchi, K., Kawatani, Y., Shibata, T., Nukiwa, T., Aburatani, H., *Yamamoto, M., and *Motohashi, H.
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Cancer Cell. 22, 66-79 (2012)
Yamazaki, H., Katsuoka, F., Motohashi, H., Engel, JD., and *Yamamoto, M.
Embryonic lethality and fetal liver apoptosis in mice lacking all three small Maf proteins.
Mol. Cell. Biol. 32, 808-816 (2012)
林 良樹(自然科学研究機構 基礎生物学研究所)
Hayashi, Y., Sexton, TR., Dejima, K., Perry, DW., Takemura, M., Kobayashi, S., *Nakato, H., and*Harrison, DA.
Glypicans regulate JAK/STAT signaling and distribution of the Unpaired morphogen.
Development 139, 4162-4171 (2012)